Description
Carnotol 500mg
Active ingredient: Disulfiram
Dosage: 500mg
Form: Tablets
Carnotol 500mg Short description:
Medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase, causing many of the effects of a hangover to be felt immediately following alcohol consumption.
Long description:
Disulfiram is used as a second-line treatment, behind acamprosate and naltrexone, for alcohol dependence.
Under normal metabolism, alcohol is broken down in the liver by the enzyme alcohol dehydrogenase to acetaldehyde, which is then converted by the enzyme acetaldehyde dehydrogenase to a harmless acetic acid derivative (acetyl coenzyme A).
Disulfiram blocks this reaction at the intermediate stage by blocking acetaldehyde dehydrogenase.
It does not reduce alcohol cravings, so a major problem associated with this drug is extremely poor compliance. Methods to improve compliance include subdermal implants, which release the drug continuously over a period of up to 12 weeks, and supervised administration practices, for example, having the drug regularly administered by ones spouse.
You should ALWAYS CONSULT YOUR PHYSICIAN and find out about the possible interactions and side effects, which may occur, before using this medication.
Long description:
Disulfiram is used as a second-line treatment, behind acamprosate and naltrexone, for alcohol dependence.
Under normal metabolism, alcohol is broken down in the liver by the enzyme alcohol dehydrogenase to acetaldehyde, which is then converted by the enzyme acetaldehyde dehydrogenase to a harmless acetic acid derivative (acetyl coenzyme A).
Disulfiram blocks this reaction at the intermediate stage by blocking acetaldehyde dehydrogenase.
It does not reduce alcohol cravings, so a major problem associated with this drug is extremely poor compliance. Methods to improve compliance include subdermal implants, which release the drug continuously over a period of up to 12 weeks, and supervised administration practices, for example, having the drug regularly administered by ones spouse.
You should ALWAYS CONSULT YOUR PHYSICIAN and find out about the possible interactions and side effects, which may occur, before using this medication.
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